Home › Essential Tremor › NCT06610877
Ultrasound Neuromodulation in Essential Tremor
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Patients with medically refractory tremor scheduled to undergo MR-guided high-intensity focused ultrasound (HIFU) thalamotomy to treat their tremor at UCSF. Exclusion Criteria: * Due to the logistical complexity of performing MRI in patients with MR-conditional pacemakers (need for device and patient monitoring), patients with pacemakers will be excluded from enrollment. All other patients undergoing HIFU thalamotomy for tremor will be eligible for enrollment.
About the study
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and measuring any associated improvement in tremor, the investigators hope to show that LIFU can be a useful tool for studying the brain circuits responsible for tremor and other brain disorders.
What is being tested
- Focused Ultrasound Neuromodulation - Sham Control (device)
- Focused ultrasound neuromodulation (device)
Sponsor: University of California, San Francisco · Participants: 60 · Started: Oct 1, 2024
Contact the study team
- Leo P. Sugrue, MD, PhD · Phone: 415-353-9056
Official record on ClinicalTrials.gov — NCT06610877
Locations in the U.S.
| California | Pritzker Building, UCSF, San Francisco |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.