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Mechanisms of Anabolic Resistance in Older Humans
RecruitingObservational studyHealthy volunteers welcome
Who can join
Ages 21 to 85 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Exclusion Criteria: 1. Diabetes or fasting plasma glucose 126 mg/dL 2. Body mass index (BMI) 30 kg/m2 3. Anemia (female subjects hemoglobin of \<11 g/dl and male subjects hemoglobin \<12 g/dl) 4. Active coronary artery disease or history of unstable macrovascular disease (unstable angina, myocardial infarction, stroke, and revascularization of coronary, peripheral or carotid artery within 3 months of recruitment) 5. Renal failure (serum creatinine \> 1.5mg/dl) 6. Chronic active liver disease (AST\>144IU/L or ALT\>165IU/L) 7. Oral warfarin group medications or history of blood clotting disorders. 8. Smoking 9. Pregnancy or breastfeeding 10. Alcohol consumption greater than 2 glasses/day or other substance abuse 11. Untreated or uncontrolled hypothyroidism 12. Debilitating chronic disease (at the discretion of the investigators)
About the study
The purpose of this research is to understand how chronic inflammation affects muscle function and responses to exercise in older adults.
What is being tested
- Exercise (other)
Sponsor: Mayo Clinic · Participants: 120 · Started: Jan 14, 2025
Contact the study team
- Rachel Passehl · Phone: 507-255-8112
Official record on ClinicalTrials.gov — NCT06617195
Locations in the U.S.
| Minnesota | Mayo Clinic, Rochester |
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.