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FIT Exercise in 30d of ULLS-induced Muscle Disuse

RecruitingHealthy volunteers welcome

Use of Velocity Monitoring to Prescribe Appropriate Flywheel-based Inertial Training (FIT) Workloads for Exercise in Space Flight

Who can join

Ages 35 to 45 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Regularly engaging in aerobic exercise (\> 150min/wk) and resistance exercise (\>1 time per week) for the past 12 months
* Education greater than or equal to bachelor's degree (any field)

Exclusion Criteria:

* Waist circumference \< 55cm or \> 90cm (F) and \< 75cm or \> 100cm (M)
* Body mass index \< 18.5 or \> 29.9
* Shoe size \< 25 or \>29cm.
* Not regularly engaging in exercise for previous 12 months
* Tobacco use within previous 6 months
* Blood clotting disorder
* Heart arrhythmia
* Implanted device which could negatively be affected by electrical impulse or strong magnetic field such as pacemaker, internal defibrillator, or cochlear implant
* Diagnosed cardiovascular, pulmonary, renal, or metabolic disease
* Pregnancy (within previous 6 months)
* Oral contraceptive use (within previous three months)
* High resting blood pressure (\>140 systolic and/or \> 90 diastolic)
* Currently or previously undergone gender-affirming therapy (hormone therapy or sexual reassignment surgery)
* Low back or leg injury in previous 6 months
* Currently taking medication to assist with sleep
* Muscle, bone, or joint injury that limits physical activity within previous 6 months
* Neurological disorder which affects balance (such as multiple sclerosis or Parkinson's disease)

About the study

This study aims to determine how flywheel-based inertial training (FIT) implemented according to principles of velocity-based training (VBT) and High-Intensity Interval Training (HIIT) affects disuse-induced physical de-conditioning including loss of voluntary muscle strength, aerobic capacity, and balance regulation.

What is being tested

Sponsor: Lance Bollinger · Participants: 16 · Started: Oct 23, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06631053

Locations in the U.S.

KentuckyUniversity of Kentucky, Lexington

Conditions

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.