Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
RecruitingHealthy volunteers welcome
Assisting Stroke Survivors With Engineering Technology (ASSET): Design Project D3: Exoskeletal Networks for Forearm Supination
Who can join
Ages 40 to 70 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria:
1. Between the ages of 40-70 (to reduce confounding effects of aging on muscle, movement accuracy and proprioception)
2. Have sustained a single, unilateral stroke at least 8 months prior to enrollment
3. Severe to moderate upper extremity impairment (ARAT score 0-30)
4. Ability to move their elbow and wrist when supported against gravity
5. Cortical stroke with hemiparesis, tactile sensation
6. Available medical records about lesion locations indicating the stroke was caused by a middle cerebral artery ischemic infarct
Exclusion Criteria:
1. Bilateral paresis
2. Diffuse/multiple lesion sites or multiple stroke events
3. Hemispatial neglect or visual field cut that prevent visual feedback
4. Shoulder pain and/or articular rigidity on the upper limb joint
5. Severe sensory deficits indicated by the Two-Point Discrimination Test
6. Botox injection to the affected upper extremity within the previous 4 months
7. Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to consent, perform the experiment, or follow commands
8. Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy
9. Other neurological issues
10. Meet any of the contraindications to Delsys Trigno Sensors:
* Implanted with electronic devices of any kind, including cardiac pace-makers or similar assistive devices, electronic induction pumps, and implanted stimulators
* Irritated skin or open wounds
* Silver allergyAbout the study
The purpose of this study is to evaluate the safety, feasibility, and efficacy of an exoskeletal network of passive, multi-joint springs for forearm supination. Also known as the forearm ExoNET, the device is a passive, robotic device that will properly assist forearm supination in the post-stroke adult population.
What is being tested
- Device tuned to Assistance (device)
- Device tuned to Sham (Slack Springs) (device)
- Device tuned to Anti-Assistance (device)
Sponsor: Shirley Ryan AbilityLab · Participants: 30 · Started: Dec 4, 2024
Contact the study team
- Valentino I Wilson · Phone: 630-398-2355
- Courtney Celian, MSOT · Phone: 312-238-1560
Official record on ClinicalTrials.gov — NCT06655636
Locations in the U.S.
| Illinois | Shirley Ryan AbilityLab, Chicago |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.