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Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

RecruitingObservational studyHealthy volunteers welcome

Who can join

Ages 18 to 100 · Women · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* 18-100 years old
* Biologically born female
* Diagnosed with EGFR positive lung cancer (Arm 1-Cancer group)
* No cancer diagnosis (Arm 2-health control)

Exclusion Criteria:

* less than 18 years of age
* Biologically born male
* Incarcerated at the time of participation

About the study

EGFR gene mutations are some of the most commonly occurring mutations in non-small cell lung cancer. Investigators have developed a DNA instability model that estimates a risk score to assess the likelihood of an individual acquiring a cancer-linked mutation. The aim of this study is to collect blood from both those diagnosed with EGFR positive lung cancer and healthy individuals, evaluate their gene sequence surrounding the EGFR landscape and use the cancer positive and healthy sequences to validate the risk assessment model, which may one day be used to provide insight on susceptibility of getting EGFR positive lung cancer or potentially other cancer types.

What is being tested

Sponsor: Our Lady of the Lake Hospital · Participants: 20 · Started: Jan 1, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06659458

Locations in the U.S.

LouisianaOur Lady of the Lake Regional Medical Center, Baton Rouge

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.