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A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery

RecruitingPhase 2Healthy volunteers welcome

Multicenter Open-Label Feasibility Study of Intraoperative Nerve and Ureter Visualization With Bevonescein in Patients Undergoing Minimally Invasive Abdominopelvic Surgery

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Must be a minimum of 18 years of age
* Study participant is planning to proceed with surgery
* Willing to provide informed consent
* Sexually active patients must be willing to use an acceptable form of contraceptive while participating and 30 days after.
* Females of childbearing potential must have a negative pregnancy test at screening and during the study.

Exclusion Criteria:

* Patient has had prior surgery at the intended surgical site.
* Patient has abnormal cardiac rhythm not controlled by medication.
* Patient has moderate to severe renal impairment.
* Patient has a history of fluorescein allergy.
* Patient has a history of drug-related anaphylactic.
* Presence of a concurrent disease or condition that may interfere with study participation.
* Presence or history of any condition that, in the view of the investigator, places the patient at high risk of treatment compliance.
* Use of any Investigational Product or investigational medial device within 30 days prior to screening.

About the study

Feasibility study of Bevonescein to highlight Nerves and Ureter in patients undergoing Minimally Invasive Surgery

What is being tested

Sponsor: Alume Biosciences, Inc. · Participants: 64 · Started: Oct 16, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06662097

Locations in the U.S.

CaliforniaUniversity of California San Diego, San Diego

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.