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Kick-Nic! Youth Quit Vaping App

RecruitingPhase 2Healthy volunteers welcome

Vaping Cessation Among Youth: Evaluating the Kick-Nic! App

Who can join

Ages 12 to 19 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

1. high school or middle school aged youth (12-19 years old),
2. regular current (past month) e-cig users using nicotine-containing e-cigs at least 1 day/week.
3. want to quit using e-cigarettes.
4. have a smartphone with data/WIFI plan in order to access and utilize the KickNic! app

Exclusion Criteria:

* Those who have non-stable (\<2 months) use of anxiolytics, antidepressants, and other psychostimulants or have a history of psychosis or any significant current psychiatric/medical condition that would increase risk will be excluded.

About the study

High school and middle school students who want to quit vaping will be randomized to receive the Kick-Nic! app or a control NCI website to determine the efficacy of the app for vaping cessation. Participants will be screened for eligibility, then go through an 8 week treatment period where they will be given access to use the Kick-Nic! app or referred to the NCI Quit Vaping website. This will be followed by 1.5, 3, 4.5 and then 6 month follow up visits. Qualitative interviews with participants and school staff will also be conducted to obtain feedback on the app and best ways to implement/disseminate the app.

Abstinence rates will be assessed biweekly during treatment including at end of treatment (EOT), and then at 1.5, 3, 4.5 and then 6 months follow ups (FU). Biochemical verification (salivary cotinine \< 30 ng.ml) of self-reports of abstinence will be conducted at EOT and 6-month FU.

What is being tested

Sponsor: Yale University · Participants: 306 · Started: Jan 7, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06662305

Locations in the U.S.

ConnecticutYale University School of Medicine (Connecticut Mental Health Center), New Haven

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.