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Feasibility and Acceptability of Primary Palliative Care Intervention in Patients Undergoing Hematopoietic Stem Cell Transplantation

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Age 18 years or older
* Undergoing autologous or allogeneic HCT at MGH

Exclusion Criteria:

* Prior receipt of inpatient specialty palliative care on two prior admissions in the past 6 months.
* Significant uncontrolled psychiatric disorders (psychotic disorder, bipolar disorder, major depression) or other co-morbid disease (dementia, cognitive impairment), which the primary oncologist believes prohibits informed consent or ability to participate in study procedures
* Inability to comprehend English as this is a preliminary/pilot study

About the study

Primary PC - or training HCT clinicians to deliver PC domains as part of routine practice - is an alternative model of supportive care. We have developed Sentinel, a primary PC intervention for HCT clinicians and patients. This study will assess Sentinel's feasibility and acceptability.

What is being tested

• Primary palliative care (behavioral)

Sponsor: Massachusetts General Hospital · Participants: 40 · Started: Jan 5, 2026

Contact the study team

• Richard A Newcomb, MD · Phone: 617-996-7584

Official record on ClinicalTrials.gov — NCT06676852

Locations in the U.S.

Conditions

• Blood Cancers

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.