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The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex
RecruitingPhase 1Healthy volunteers welcome
Who can join
Ages 18 to 30 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Possess a current drivers' license * Driven a motor vehicle at least once in the past 30 days * Able to read English * Test negative for all substances on a urine drug test and complete a test drive to ensure the absence of simulation sickness * Not taking any daily prescription medications (excluding birth control) * Not diagnosed with any serious chronic disease by a licensed healthcare provider (including but not limited to Alzheimer's and related dementias, Parkinson's disease or other neurodegenerative disorder, major depressive or anxiety disorder, schizophrenia or other serious mental illness, arrhythmias, cataracts, glaucoma, chronic obstructive pulmonary disease, diabetes, epilepsy, sleep apnea, and fibromyalgia) * Have an individual willing to drive them home after testing or be taken home by study staff after testing Exclusion Criteria: * Currently smoke, vape or use tobacco products, used CBD in the past 30 days * Used illegal drugs in the past 30 days (e.g., cocaine/crack, heroin, methamphetamine, 3,4-methylenedioxy-methamphetamine, inhalants, phencyclidine, lysergic acid diethylamide, psilocybin mushrooms, or marijuana) * Are pregnant or lactating at time of study
About the study
The objectives/purpose of this study are to comprehensively investigate the effects of non-prescription CBD on driving performance, drowsiness, sedation, and cognitive function in a large sample of healthy adults aged 18-30 years, with additional characterization of effects by dose and by sex, using a rigorous RCT design which will naturally mitigate confounding factors.
What is being tested
- Cannabidiol (CBD) Oil 300mg (drug)
- Cannabidiol (CBD) Oil 150mg (drug)
- Placebo Oil (drug)
Sponsor: West Virginia University · Participants: 300 · Started: Jun 30, 2025
Contact the study team
- Toni M Rudisill, PhD · Phone: 3042930687
Official record on ClinicalTrials.gov — NCT06686914
Locations in the U.S.
| West Virginia | West Virginia University, Morgantown |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.