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Next-Generation Photon-Counting CT Technology: Development and Clinical Evaluation

Who can join

Ages 18 to 89 · All sexes

Inclusion Criteria:

* Age 18 to 89.
* Participants must be informed of the investigational nature of this study and be willing to provide written informed consent and participate in this study in accordance with institutional and federal guidelines prior to study-specific procedures.
* Not pregnant (based on attestation)

Exclusion Criteria:

* Pregnant women will not be included. All females of childbearing potential must attest that they are not pregnant before CT imaging.
* Participants with a known contrast allergy.
* Any current medical condition, illness, or disorder, as assessed by medical record review and/or self-reported, that is considered by a physician investigator to be a condition that could compromise participant safety or successful participation in the study.

About the study

This project aims to develop and evaluate a next-generation photon-counting CT prototype, and assess whether next-generation photon-counting CT--which enables reduced radiation dose, high spatial resolution, and spectral imaging--would facilitate improved diagnostic performance for abdominal, cardiothoracic, musculoskeletal, and neuroimaging.

What is being tested

• CT-DACE (diagnostic test)

Sponsor: University of Pennsylvania · Participants: 250 · Started: Nov 19, 2024

Contact the study team

• Erin Schubert · Phone: 215-573-6569
• Hannah Straughn · Phone: 443-739-4971

Official record on ClinicalTrials.gov — NCT06691659

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.