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An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors

Feasibility and Acceptability of an Individualized Online Home-Based Exercise Program on Psychoneurological Symptoms in Gynecologic Cancer Survivors: A Pilot Study

Who can join

Ages 18 and older · Women

Inclusion Criteria:

* Women aged ≥ 18 years old
* Previously diagnosed with gynecologic cancer (e.g., uterine, ovarian, cervical)
* Completed cancer treatment (chemotherapy or chemoradiation)
* Able to read and speak English
* Do not meet recommended exercise levels as defined by The American College of Sports Medicine

Exclusion Criteria:

* History of metastatic or other primary cancer
* Serious mental health conditions (e.g., bipolar disorder, schizophrenia, major depression)
* Certain chronic diseases (e.g., muscular-skeletal diseases that limit mobility, autoimmune diseases, uncontrolled diabetes, hypertension, renal disease (creatinine \> 2.5 mg/dL)
* Unable to read/speak English

About the study

This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such as pain, fatigue, sleep disturbance, depression, and cognitive impairment. These symptoms can significantly reduce the quality of life (QoL) and survival rate in this cancer population. Thus, promoting physical activity among cancer survivors may help mitigate these severe symptoms. Using online platforms such as Zoom can help participants access an individualized exercise program that meets their specific needs to engage in physical activity and decrease their symptom burden. Home-based exercise, by providing self-chosen time and location and low costs, can address some barriers to physical activity for cancer survivors. An individualized online home-based exercise program may be feasible, and may improve symptoms and quality of life in gynecologic cancer survivors.

What is being tested

• Exercise Intervention (other)
• Functional Assessment (other)
• Medical Device Usage and Evaluation (other)
• Questionnaire Administration (other)
• Supportive Care (other)

Sponsor: Emory University · Participants: 40 · Started: Sep 1, 2025

Contact the study team

• Zahra Barandouzi, Ph.D.,MSN,RN · Phone: 4045449078

Official record on ClinicalTrials.gov — NCT06709534

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.