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Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism
Who can join
Ages 18 to 65 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Overweight/Obese (BMI ≥25) * Sedentary Lifestyle: Physical Activity Level\<1.4 * Less than 150min/week of structured Exercise Exclusion Criteria: * Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications * Excessive alcohol, drug abuse, smoking * Pregnant Women * Unwilling to adhere to the study Intervention
About the study
Once written consent is obtained, the participant will be provided with an accelerometer to be worn for 7 days to assess current physical activity levels. Subjects will be provided with a standardized diet (55/15/30% CHO/PRO/FAT) prior to collection of pre-intervention data of insulin sensitivity. Individuals will then participate in an 8-week electrical stimulation intervention (30min/day, 3x/week) and randomized into placebo/control, NMES, resistance training combined with NMES (RT +NMES), or resistance training (RT) group (n=20 per group), followed by collection of post-intervention data. The control group will receive electrical stimulation up to sensory level, the NMES group will receive stimulation up to tolerable intensity to induce visible muscle contraction, the RT+ NMES will receive stimulation up to tolerable intensity during resistance training, and the RT group will only receive exercise training. Control and NMES group will self administer stimulation at home. Pre-and post-intervention data includes measurements for body composition, resting metabolic rate, VO2max, insulin sensitivity, and comprehensive blood work.
What is being tested
- Neuromuscular Electrical Stimulation (Sensory) (device)
- Neuromuscular Electrical Stimulation (device)
- Resistance Training (other)
Sponsor: University of Texas, El Paso · Participants: 80 · Started: Aug 19, 2024
Contact the study team
- Sudip Bajpeyi, PhD · Phone: 9157475461
Official record on ClinicalTrials.gov — NCT06722391
Locations in the U.S.
| Texas | University of Texas at El Paso, El Paso |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.