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Exploring Neurophysiological Markers of Brain Health

RecruitingHealthy volunteers welcome

Exploring Markers of Brain Health With EEG and TMS: A Pilot Study

Who can join

Ages 22 to 100 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Must be an active brain imaging participant in The BrainHealth Project (NCT04869111)
* Minimum age of 22
* Fluent in English
* Able to read \& hear information over a computer
* Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center.
* Must pass a modified TMS Adult Safety Screen
* Meet all criteria for study as determined by the study physician

Exclusion Criteria:

* A diagnosis of a neurodegenerative disease
* A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level
* A diagnosis of autism spectrum disorder that currently hinders them from functioning independently.
* Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants)
* Magnetically activated implants or electronically implanted devices
* Medication pumps
* Personal or family history of epilepsy, seizure(s), seizure disorder.
* History of, or risk factors for syncope (fainting)
* Report significant cognitive challenges
* Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism)
* Have claustrophobia

About the study

The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) has been suggested as a promising brain imaging tool for identifying biomarkers of brain health.

In this pilot study, study investigators will explore the neurophysiological metrics of brain health with a non-invasive brain imaging technique, alongside behavioral and fMRI metrics collected through another study (NCT04869111).

What is being tested

Sponsor: The University of Texas at Dallas · Participants: 63 · Started: Sep 3, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06731452

Locations in the U.S.

TexasCenter for BrainHealth at The University of Texas at Dallas, Dallas

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.