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Exploring Neurophysiological Markers of Brain Health
Exploring Markers of Brain Health With EEG and TMS: A Pilot Study
Who can join
Ages 22 to 100 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Must be an active brain imaging participant in The BrainHealth Project (NCT04869111) * Minimum age of 22 * Fluent in English * Able to read \& hear information over a computer * Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center. * Must pass a modified TMS Adult Safety Screen * Meet all criteria for study as determined by the study physician Exclusion Criteria: * A diagnosis of a neurodegenerative disease * A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level * A diagnosis of autism spectrum disorder that currently hinders them from functioning independently. * Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants) * Magnetically activated implants or electronically implanted devices * Medication pumps * Personal or family history of epilepsy, seizure(s), seizure disorder. * History of, or risk factors for syncope (fainting) * Report significant cognitive challenges * Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism) * Have claustrophobia
About the study
The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) has been suggested as a promising brain imaging tool for identifying biomarkers of brain health.
In this pilot study, study investigators will explore the neurophysiological metrics of brain health with a non-invasive brain imaging technique, alongside behavioral and fMRI metrics collected through another study (NCT04869111).
What is being tested
- Strategic Memory Advanced Reasoning Training teaches meta-cognitive strategies for individuals to apply to their daily lives for improved performance (behavioral)
Sponsor: The University of Texas at Dallas · Participants: 63 · Started: Sep 3, 2025
Contact the study team
- Erin Venza, MS · Phone: 972-883-3208
Official record on ClinicalTrials.gov — NCT06731452
Locations in the U.S.
| Texas | Center for BrainHealth at The University of Texas at Dallas, Dallas |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.