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Navicam for Detection of Barrett's Esophagus

Recruiting

Use of a Detachable String Capsule for Evaluation of Barrett's Esophagus

Who can join

Ages 22 and older · All sexes

Full eligibility criteria
Inclusion Criteria

* Adults greater than or equal to 22 years of age with or without Barrett's Esophagus
* All Patients:

  o Have had an endoscopy within 1 year of baseline enrollment
* Patients with Barrett's Esophagus:

  * Presence of at least 1cm of salmon colored mucosa with corresponding biopsies showing intestinal metaplasia who are treatment naïve and undergoing surveillance Or
  * Chronic Gastro Esophageal Reflux Disease (GERD) patients with at least 3 additional risk factors that meet Barrett's Esophagus screening criteria per latest clinical guidelines

Exclusion Criteria

* Inability to comprehend or read the consent form
* Have an oropharynx, esophageal, or gastro-esophageal tumor
* Ongoing symptoms of dysphagia
* Presence of active clinically significant stricture
* History of stricture requiring dilation
* Presence of pacemaker or implanted cardiac defibrillator
* History of esophageal surgery with the exception of fundoplication
* Pregnancy
* History of surgery or obstructive process of the small bowel
* BMI \> 38

About the study

Using a non-invasive capsule system to achieve optimal viewing angles of the esophagus for detection of Barrett's esophagus

What is being tested

Sponsor: Mayo Clinic · Participants: 57 · Started: Feb 20, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06748911

Locations in the U.S.

FloridaMayo Clinic in Florida, Jacksonville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.