The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

Recruiting

Who can join

Ages 18 and older · All sexes

Full eligibility criteria

Inclusion Criteria:

Participant must be ≥ 18 years of age. Participant must self-identify as Black and/or Latino. Participant must be an oncology patient at a participating NCORP. Participant must be eligible to participate in an ECOG-ACRIN clinical trial. Participant must have the ability to understand and the willingness to sign a e-consent document.

Participant must be receiving care at a participating NCORP affiliated community oncology site.

Participant must be English or Spanish speaking to be eligible. Participant must have access to a landline, smartphone, computer, or tablet.

Exclusion Criteria:

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About the study

The purpose of this study is to conduct a Hybrid Type 1 cluster-randomized, roll-out effectiveness-implementation trial in NCORP community oncology practice sites (N= 500 Black and Latino cancer patients) to evaluate the effectiveness of the EA SUPPORT intervention combining CT navigators and CT research literacy tools in improving Black and Latino patient referral and accrual to NCI-supported CTs (primary outcomes) and participant and provider awareness and knowledge of CTs (secondary outcomes) while assessing implementation factors. Also, with the CUSP2CT data, Evaluation, and Coordinating Center, conduct final site evaluation and disseminate the SUPPORT intervention to NCORP community oncology sites, research bases, and affiliated trial networks.

What is being tested

SUPPORT toolkit (other)

Sponsor: Eastern Cooperative Oncology Group · Participants: 500 · Started: Apr 25, 2025

Contact the study team

Melissa A Simon, MD, MPH · Phone: (312) 503-8780
Elyse R Park, PhD, MPH · Phone: (617) 724-6836

Official record on ClinicalTrials.gov — NCT06756607

Locations in the U.S.

Arkansas	NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro, Jonesboro
Georgia	Liberty County Cancer Care, Hinesville Regional Cancer Care - Jessup, Jesup Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Savannah
Illinois	Rush-Copley Medical Center, Aurora Advocate Good Shepherd Hospital, Barrington Carle BroMenn Outpatient Center, Bloomington Advocate Illinois Masonic Medical Center, Chicago AMG Crystal Lake - Oncology, Crystal Lake Carle at The Riverfront, Danville Advocate Good Samaritan Hospital, Downers Grove Carle Physician Group-Effingham, Effingham Advocate Sherman Hospital, Elgin Advocate South Suburban Hospital, Hazel Crest AMG Libertyville - Oncology, Libertyville Condell Memorial Hospital, Libertyville Carle Physician Group-Mattoon/Charleston, Mattoon Carle BroMenn Medical Center, Normal Carle Cancer Institute Normal, Normal Advocate Christ Medical Center, Oak Lawn Advocate Outpatient Center - Oak Lawn, Oak Lawn Advocate Lutheran General Hospital, Park Ridge Carle Cancer Center, Urbana Rush-Copley Healthcare Center, Yorkville
Mississippi	Baptist Memorial Hospital and Cancer Center-Golden Triangle, Columbus Baptist Cancer Center-Grenada, Grenada Baptist Memorial Hospital and Cancer Center-Union County, New Albany Baptist Memorial Hospital and Cancer Center-Oxford, Oxford Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven
New York	Montefiore Medical Center - Moses Campus, The Bronx Montefiore Medical Center-Einstein Campus, The Bronx
Pennsylvania	Geisinger Medical Center, Danville Geisinger Cancer Center Dickson City, Dickson City Geisinger Medical Center-Cancer Center Hazleton, Hazleton Geisinger Medical Oncology-Lewisburg, Lewisburg Geisinger Cancer Services-Pottsville, Pottsville Community Medical Center, Scranton Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre
South Carolina	Saint Joseph's/Candler - Bluffton Campus, Bluffton South Carolina Cancer Specialists PC, Hilton Head Island The Radiation Oncology Center-Hilton Head/Bluffton, Hilton Head Island
Tennessee	Baptist Memorial Hospital and Cancer Center-Collierville, Collierville Baptist Memorial Hospital and Cancer Center-Memphis, Memphis Baptist Memorial Hospital for Women, Memphis
Virginia	Bon Secours Memorial Regional Medical Center, Mechanicsville Bon Secours Saint Francis Medical Center, Midlothian Bon Secours Westchester Emergency Center, Midlothian Bon Secours Cancer Institute at Reynolds Crossing, Richmond Bon Secours Richmond Community Hospital, Richmond Bon Secours Saint Mary's Hospital, Richmond
Wisconsin	Aurora Cancer Care-Southern Lakes VLCC, Burlington Aurora Saint Luke's South Shore, Cudahy Aurora Health Care Germantown Health Center, Germantown Aurora Cancer Care-Grafton, Grafton Aurora BayCare Medical Center, Green Bay Aurora Cancer Care-Kenosha South, Kenosha Aurora Bay Area Medical Group-Marinette, Marinette Aurora Cancer Care-Milwaukee, Milwaukee Aurora Saint Luke's Medical Center, Milwaukee Aurora Sinai Medical Center, Milwaukee Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh Aurora Cancer Care-Racine, Racine Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan Aurora Medical Center in Summit, Summit Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers Aurora Cancer Care-Milwaukee West, Wauwatosa Aurora West Allis Medical Center, West Allis

Conditions

Cancer (all types)

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.