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Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement
Recruiting
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * had a knee replacement (including primary, staged or independent bilateral, or revision) at least 12 months ago * have a computer, tablet, or smartphone with active internet access * self-report engaging in less than 60 minutes/week of moderate-intensity physical activity * be English-speaking and able to read consent and study materials written in English * be willing to complete the 4 remote assessments, including physical activity monitoring * be willing to be randomized to receive 0-4 supplemental intervention components. Exclusion Criteria: * any contraindications to physical activity (e.g., chest pain) * have a scheduled surgery within the next 12 months (e.g., hip or knee replacement) * have a mobility limiting comorbidity unrelated to knee replacement * live outside of the continental U.S * do not currently have a physician or orthopedic surgeon whom they see regularly * are currently participating in physical therapy (for knee) * are participating in a structured weight loss or physical activity program * unable to provide proof of knee replacement surgery * have a BMI \>40kg/m2 * score \>30 on PROMIS cognitive function
About the study
The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.
What is being tested
- Phone Coaching (behavioral)
- Progress reports to providers (behavioral)
- 'Hear from Others' Videos (behavioral)
- Individualized Feedback (behavioral)
- Online exercise program (behavioral)
Sponsor: University of South Carolina · Participants: 336 · Started: Jan 21, 2025
Contact the study team
- Jakob Nelson, MS · Phone: 803-766-6960
- Christine Pellegrini, PhD · Phone: 803-777-0911
Official record on ClinicalTrials.gov — NCT06768762
Locations in the U.S.
| South Carolina | University of South Carolina, Columbia |
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.