Home › Left Ventricular Dysfunction › NCT06770062
Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study
RecruitingObservational study
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Age \>= 18 * Male or Female * A diagnosis of severe chronic primary mitral regurgitation * Undergoing isolated robotic mitral annuloplasty at Mayo Clinic Rochester * Patients must have the ability to consent or have an appropriate representative available to do so. Exclusion Criteria: * Prior valve intervention, * Concomitant valve surgery at the time of mitral annuloplasty (e.g. tricuspid annuloplasty, aortic valve replacement). * Concomitant \>= moderate regurgitation or stenosis in any other valve by preoperative echocardiography * History of prior myocardial infarction * History of cardiomyopathy unrelated to mitral regurgitation (e.g. dilated, hypertrophic, infiltrative) * Pregnancy. Women of childbearing potential will be verbally screened by clinical staff during as part of routine pre-MRI evaluation. If a subject is unsure whether they could be pregnant, a negative pregnancy test will be performed prior to scanning. * Implantable devices that would be a contraindication to MRI * Severe allergy to gadolinium MRI contrast
About the study
The purpose of this research is to determine the feasibility of a larger, future study proposing a multimodal approach using cardiac CT and MRI to assess the risk of developing left ventricular (LV) systolic dysfunction in patients with mitral regurgitation (MR).
What is being tested
- Cardiac MRI (diagnostic test)
Sponsor: Mayo Clinic · Participants: 30 · Started: Jan 20, 2025
Contact the study team
- Cardiovascular Surgical Research · Phone: (507) 266-7982
Official record on ClinicalTrials.gov — NCT06770062
Locations in the U.S.
| Minnesota | Mayo Clinic, Rochester |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.