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Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep

The Impact of Nasal Versus Oral Breathing on Measures of Drug-Induced Sleep Endoscopy

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* • Adults (≥ 18yrs) that underwent clinical evaluation at the CPAP Alternatives Clinic at Penn Otorhinolaryngology.

  * Must have at least mild OSA (AHI\>5)

Exclusion Criteria:

* • Sleep study with an AHI\<5, \>25% of total events being central or mixed events, or inability to achieve adequate drug-induced sleep.

  * Upper Respiratory Illness at the time of the DISE.

About the study

This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.

Sponsor: University of Pennsylvania · Participants: 50 · Started: Nov 20, 2024

Contact the study team

• Everett Seay · Phone: 215-662-2777

Official record on ClinicalTrials.gov — NCT06789770

Locations in the U.S.

Conditions

• Obstructive Sleep Apnea

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.