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Dysregulation of Whole-body Metabolism in Ovarian Cancer: A Longitudinal Study

RecruitingObservational study

Who can join

Ages 18 and older · Women

Full eligibility criteria
Inclusion Criteria:

* Women
* Age \>18
* Presumed ovarian cancer diagnosis (i.e. those being clinically evaluated for suspicion of ovary cancer)
* Planned treatment course for ovarian cancer involving cytoreductive surgery followed by chemotherapy
* Availability to commit to attending all study visits
* Internet access and consistent access to phone/email/text communication

Exclusion Criteria:

* Pregnancy
* Inability to provide voluntary informed consent
* Inability to consume the pre-study visit meal/snack and/or the study visit meal due to strict dietary restrictions
* Illicit substance use (e.g. cocaine, methamphetamines, heroin, street drugs) - marijuana and CBD oil and related supplements will be considered on a case-by-case basis by the principal investigators
* Circumstances and/or medical condition that would limit compliance with study requirements and protocol, as determined by the principal investigators

About the study

Minimal information is available regarding changes in whole-body metabolism in ovarian cancer patients, and no study has assessed whole-body lipid metabolism in this patient population. In this pilot study we will assess fasting and postprandial lipid metabolism of ovarian cancer patients before, during, and after treatment via indirect calorimetry.

What is being tested

Sponsor: University of Tennessee Graduate School of Medicine · Participants: 10 · Started: Mar 22, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT06800105

Locations in the U.S.

TennesseeUniversity of Tennessee Graduate School of Medicine, Knoxville

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.