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Growth Hormone for the Treatment of Gastroparesis

RecruitingEarly phase 1

Low-dose Growth Hormone for the Treatment of Gastroparesis

Who can join

Ages 18 to 65 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Symptoms \> 6 months that have not responded satisfactorily to standard treatment.
* For gastroparesis: Gastroparesis Cardinal Symptom Index (GCSI) score of \>21

Exclusion Criteria:

* Known history of GH deficiency, hypothalamic or pituitary disease
* Diabetes
* Prior use of GH therapy
* Age-adjusted low serum IGF1
* Women on oral estrogen therapy6
* Pregnancy or nursing
* History of malignant solid tumors
* Obesity (BMI \> 30)History of coronary and thromboembolic diseases.
* History of sarcoidosis
* History of pituitary surgery
* History of thyroid nodules.
* Any other condition, which in the opinion of the investigator would impede compliance or hinder completion of the study.
* Failure to give informed consent.

About the study

The purpose of this study is to determine whether treatment with Growth Hormone results in symptomatic improvement in patients with gastroparesis.

What is being tested

Sponsor: Mayo Clinic · Participants: 10 · Started: Oct 22, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06803589

Locations in the U.S.

ArizonaMayo Clinic, Phoenix
Mayo Clinic in Arizona, Scottsdale

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.