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Diagnosis and Treatment of Urinary Tract Infection Using DNA Polymerase Chain Reaction Versus Urine Culture
Diagnosis and Treatment of Urinary Tract Infection Using DNA PCR Versus Urine Culture - A Randomized Controlled Trial
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Adult men and women 18 years and older * Presenting to clinic with symptoms of UTI or cystitis * Patients with Medicare and Medicaid insurance Exclusion Criteria: * Urinary diversion of any type * Chronic indwelling urinary catheter * Diagnosed UTI within the previous 21 days * Antibiotic therapy within the previous 21 days * Use of phenazopyridine within the previous 21 days * Commercial insurance * Non-English speaking * Pregnant patients
About the study
Adults 18 years or older with urinary tract infection (UTI) symptoms. Participants will be assigned to either the urine culture group or the DNA PCR study group by randomization. At time of enrollment in the study they will be also asked to fill out two questionnaires. If prescribed antibiotics for treatment of a UTI, participants will then be called the day after they are scheduled to stop their antibiotics. Participants will be asked to fill out questionnaires the day after finishing antibiotics. Participants will be enrolled in the study for a maximum of 21 days.
What is being tested
- DNA PCR (device)
- Urine Culture (diagnostic test)
Sponsor: University Hospitals Cleveland Medical Center · Participants: 136 · Started: Oct 22, 2025
Contact the study team
- Diana N Mitchell, MD, MBA, BSN · Phone: 216-844-1000
Official record on ClinicalTrials.gov — NCT06808451
Locations in the U.S.
| Ohio | University Hospitals, Cleveland |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.