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Pneumatic Compression vs Blood Flow Restriction for Muscle Recovery

RecruitingHealthy volunteers welcome

Comparing the Effects of Pneumatic Compression and Blood Flow Restriction Therapy on Muscle Recovery

Who can join

Ages 18 to 30 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* 18-30 years of age
* Recreationally active population
* Women should be on a form of hormonal contraception.
* No current musculoskeletal injuries or pathologies
* Must answer "yes" to all PAR-Q questions.

Exclusion Criteria:

* Individuals that routinely train trail running
* Discomfort when running
* Deep vein thrombosis
* Blood clots
* Cancerous lesions
* Sensory or mental impairment
* Unstable fractures
* Acute pulmonary edema
* Acute thrombophlebitis
* Acute congestive cardiac failure
* Acute infections
* Episodes of pulmonary embolism
* Wounds, lesions, infection, or tumors
* Bone fractures or dislocations
* Increased venous and lymphatic return
* Answers "no" to any of the PAR-Q screening questions

About the study

Both BFR and intermittent pneumatic compression are purported to decrease symptoms associated with exercise induced muscle damage (EIMD) that cause delayed onset muscle soreness (DOMS). Blood flow restriction relies on applying pressurized cuffs to the most proximal portion of the limb. Another form of recovery often relied upon is pneumatic compression. The mechanism by which pneumatic compression works is similar to that of a massage, whereby the device progressively increases the pressure on a portion of the limb before releasing and moving further up the limb.The purpose of this study is determine whether BFR or pneumatic compression can be used to decreased DOMS which may indicate enhanced recovery.

What is being tested

Sponsor: University of Southern California · Participants: 33 · Started: Jan 15, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06815367

Locations in the U.S.

CaliforniaUniversity of Southern California, Los Angeles

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.