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Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients

Effects of Photobiomodulation on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients

Who can join

Ages 5 to 17 · All sexes

Inclusion Criteria:

* Patient/guardian speaks either English or Spanish
* Patient presenting with one or more aphthous ulcers in their mouth, identified during a scheduled dental appointment
* No previous PBM treatment to the presenting aphthous ulcer(s)
* Guardian able to partake in a follow-up phone call in either the English or Spanish language

Exclusion Criteria:

* Patient presents with aphthous ulcers recently treated with PBM
* Patient presents with herpes labialis (cold sores)
* Patients presents with systemic disease that affects soft tissue/mucous healing

About the study

The purpose of this study is to compare the efficacy of laser photobiomodulation and "Magic Mouthwash" for treatment of pain in pediatric patients with aphthous ulcers , to assess how photobiomodulation influences the rate of healing of aphthous ulcers in pediatric patients and to measure changes in pain levels reported by pediatric patients undergoing photobiomodulation treatment for aphthous ulcers.

What is being tested

• PBM Therapy (device)
• Maalox plus Benadryl (drug)

Sponsor: The University of Texas Health Science Center, Houston · Participants: 30 · Started: Mar 10, 2025

Contact the study team

• Brett Chiquet, DDS, PhD · Phone: (713) 500-8220
• Jessica Hochschuler · Phone: (713) 486-4141

Official record on ClinicalTrials.gov — NCT06819033

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.