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Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

Evaluating Q-Collar Effects on Cerebrovascular Control in Response to Exercise

Who can join

Ages 18 to 30 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* healthy individuals between the ages of 18 to 30 years old

Exclusion Criteria:

* History of concussion or other brain injury resulting in loss or alteration in consciousness or other change in cognition within 24 months of study visit
* High cardiac risk according to the American College of Sports Medicine (ACSM)11
* Ongoing active treatment with a cardioactive drug
* Inability to stand from a seated position unassisted
* History of a neurologic disorder or neurosurgery intervention
* Pregnancy
* Any current, serious, chronic medical or psychiatric disease that in the Principal Investigator's or co-investigator's judgment may interfere with study participation or data integrity
* Unable or unwilling to provide informed consent

About the study

The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are:

1. How does the Q-Collar affect brain blood flow when there are quick changes in blood pressure, like when standing up quickly, or when breathing against resistance? 2. How does the Q-Collar affect brain blood flow during exercise?

Researchers will compare sessions where participants wear the Q-Collar to sessions where they do not wear the device to see if the Q-Collar improves brain blood flow during both rest and exercise.

Participants will:

* Complete two study visits, each 1 to 4 weeks apart. * Perform a series of tasks, including standing tests, breathing tests, and exercise on a stationary bike, while their heart rate, brain blood flow, and other body functions are monitored. * Wear the Q-Collar during one of the sessions and not wear it during the other session. The order of the sessions will be randomly assigned.

What is being tested

• Q30 Q-Collar (device)
• Not wearing Q-Collar (other)

Sponsor: Spaulding Rehabilitation Hospital · Participants: 20 · Started: Jul 23, 2025

Contact the study team

• J. Andrew Taylor, MS, PhD · Phone: 617-758-5503

Official record on ClinicalTrials.gov — NCT06826781

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.