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Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression

RecruitingHealthy volunteers welcome

Who can join

6 Months · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* The high-risk group (n = 150) will consist of women with at least one episode of MDD since their baby's birth.
* To qualify for the low-risk group (n = 75), women cannot have a history of any depressive disorder or any current psychiatric diagnoses.
* Infants will be required to be singleton children born full-term (\> 37 weeks) and normal weight (\> 2,500 grams) with no birth complications or health problems to avoid medical complications contributing to infants' attention, reactivity, and regulation measures.
* The two groups will be matched on demographic factors (e.g., age, race/ethnicity, income).

Exclusion Criteria:

* Additional exclusion criteria are diagnoses of alcohol or substance use disorders currently or at any point during pregnancy, or lifetime history of bipolar or psychotic disorders.

About the study

The goal of this study is to examine attentional biases for facial displays of emotion as a mechanism of risk in infants of mothers with postpartum major depression, and the potential role of infant arousal in the development of these attentional biases.

What is being tested

Sponsor: Binghamton University · Participants: 225 · Started: Nov 14, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06835855

Locations in the U.S.

New YorkBinghamton University, Binghamton

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.