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Identifying Changes in Food Behaviors Associated With Beginning GLP-1 Medication

RecruitingObservational study

Exploring the Influence of GLP-1 Medication on Food Attitudes and Selection in a Virtual Reality Buffet

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Adults (18+) with overweight or obesity (BMI \>25 kg/m2)
* Not currently taking an incretin-based medication at baseline
* Recently (within two weeks) prescribed a GLP-1, can be included if they have a obesity-related co-occurring condition (diabetes, hypertension, cardiovascular disease, dyslipidemia)
* Have had no prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy.
* Fluent in English

Exclusion Criteria:

* Adults (18+) without overweight or obesity
* \<18 years of age at time of testing
* Adults not taking a GLP-1 Medication
* Adults taking a compound GLP-1
* Adults on GLP-1 medication for longer than 2 weeks at baseline
* Have had a prior diagnosis of cognitive or physical disability, dyslexia, or epilepsy.
* Not fluent in English

About the study

In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss. Little is known, however, about how these medications may alter an individual's attitude towards food, food reactivity, or the specific types and amounts of foods an individual will choose. The purpose of this study is to observe the changes an individual experiences in their relationship and reaction to food and in their food selection prior to or within the first two weeks of taking GLP-1 medication to after three months on the medication. The researchers of this study believe that an understanding of such changes can inform questions seeking to ensure maintenance of appropriate nutrient balance within individuals on weight loss medications.

What is being tested

Sponsor: Penn State University · Participants: 25 · Started: Jul 15, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06843512

Locations in the U.S.

PennsylvaniaHealth, Ingestive Behavior, and Technology Laboratory of Pennsylvania State University, State College

Conditions

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.