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Peri-operative Tamsulosin and Impact on Voiding Trial After Same-day Urogynecology Surgery

Peri-operative Tamsulosin and Impact on Voiding Trial Following Outpatient Urogynecology Surgery: a Randomized Controlled Trial

Who can join

Ages 18 and older · Women

Inclusion Criteria:

\- Patients undergoing any pelvic organ prolapse repair or incontinence surgery

Exclusion Criteria:

* Any surgery involving a non-urogynecologist
* Patients already on an alpha blocker
* Baseline hypotension
* History of syncope
* Postural orthostatic tachycardia syndrome (POTS)
* Non-English speaker or interpreter unavailable for Spanish-speaking patient
* Impaired cognition impeding proper consenting
* Any other medical contraindication for tamsulosin use
* History of urinary retention requiring continuous or intermittent catheterization
* Patients consented for the study but then due to intraoperative complication, routine voiding trial no longer indicated due to requiring indwelling catheter or intermittent catheterization on discharge will be excluded from primary outcome analysis
* Pregnancy

About the study

The purpose of this research study is to determine if taking tamsulosin preoperatively decreases your chances of being discharged after surgery with a Foley catheter (flexible tube that drains urine from the bladder into a collection bag).

What is being tested

• Tamsulosin (drug)
• Placebo (drug)

Sponsor: TriHealth Inc. · Participants: 166 · Started: Feb 3, 2025

Contact the study team

• Gisele C Moran, MD, MPH · Phone: 513-862-1123

Official record on ClinicalTrials.gov — NCT06843538

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.