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Treatment of Upper Gastrointestinal Symptoms Using Hypnotherapy Sessions
Recruiting
The Impact Of Gastric Phenotyping In Predicting And Assessing The Clinical Success Of Gut-Directed Hypnotherapy For Patients With Gastroduodenal DGBIS.
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion criteria: * Patients will meet criteria for at least one upper GI DGBI including functional dyspepsia, any nausea/vomiting disorder, or functional abdominal bloating. Lower GI DGBIs, such as IBS, are allowable if the primary symptom is either an upper GI symptom or bloating/distension. * Participants will have had a negative 4-hour solid food gastric emptying test previously or a normal C13 Breath test at screening. * Patients with known disaccharide intolerances may be included if dietary restrictions are maintained during the duration of the study. * Patients utilizing cannabinoid based substances may be included if no dose changes are made during the duration of the study * Patients will be proficient in English language for comprehension of content * Patients will have reliable access to digital delivery systems for content and questionnaire access via smartphone over the course of the study and follow up period. Exclusion criteria: * Patients with known current diagnosis of small intestinal bacterial overgrowth (SIBO), gastroparesis, rumination syndrome, chronic intestinal pseudo-obstruction, advanced connective tissue diseases (e.g. scleroderma), and uncontrolled inflammatory bowel disease (IBD) will be excluded. * Patients with current untreated H. pylori infection will be excluded. * In patients with predominant bloating symptoms and constipation, those with untreated pelvic floor dysfunction will be excluded. If the predominant symptoms are nausea/vomiting or dyspepsia, or if constipation is not present, then pelvic floor dysfunction will not be exclusionary. * Patients who have a history of cognitive delay, traumatic brain injury with residual deficits, history of cerebral vascular accident with residual deficiencies in cognition, dementia, shall be excluded * Patients with significant psychiatric illness with component of psychosis (schizophrenia, bipolar disorder), as well as severe untreated major depressive disorder with suicidal ideation will be excluded * Patients with substance abuse disorders and drug addiction will be excluded. * Patients who are unlikely to comply or unlikely to benefit from psychotherapy-based interventions may be excluded at the direction of medical screening provider or principal investigator. * Standard inclusion criteria will include: ability to provide informed consent, absence of other diseases (structural or metabolic) which could interfere with interpretation of the study results. * Stable doses medications are permissible, but dosing should not be changed during study period. * Patients who are pregnant.
About the study
The purpose of this research is to evaluate if hypnotherapy delivered digitally will help your GI symptoms.
What is being tested
- Hypnotherapy (behavioral)
- Educational module (behavioral)
Sponsor: Mayo Clinic · Participants: 100 · Started: Feb 20, 2025
Contact the study team
- Taylor Hines · Phone: 507-538-9959
Official record on ClinicalTrials.gov — NCT06846359
Locations in the U.S.
| Minnesota | Mayo Clinic, Rochester |
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.