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Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries

Recruiting

Function And Speed of Transection Recovery After Therapeutic Electrostimulation of Nerves

Who can join

Ages 18 to 80 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Age 18-80 years
* Candidate for surgical intervention under general anesthesia.
* Require primary nerve injury repair in at least 1 digital nerve.
* Following resection, have a resulting nerve gap of ≤ 10mm.
* Able to complete tension-free end-to-end direct repair, or repair with a conduit, autograft, or allograft with a length ≤15mm
* Signed and dated informed consent form.

Exclusion Criteria:

* Severe comorbid conditions, such as arrhythmia or congestive heart failure, preventing surgery under general anesthesia.
* Nerve repair occurring \>1 month post-injury.
* Incomplete nerve transection.
* Injury requiring replantation of target digit
* Injury distal to the distal interphalangeal joint.
* Injury proximal to branching into the proper or common digital nerves.
* Injuries to both digital arteries of an affected digit.
* History of neuropathy, diabetic neuropathy, or any other known neuropathy
* History of chronic ischemic condition of the upper extremity
* Cognitive impairment preventing the ability to provide consent, follow post-operative instructions, or complete clinical assessments.

About the study

The goal of this clinical study is to evaluate if a period of electrical stimulation delivered during the surgical repair procedure can speed up nerve healing.

What is being tested

Sponsor: Checkpoint Surgical Inc. · Participants: 60 · Started: Apr 24, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06867185

Locations in the U.S.

IndianaIndiana Hand to Shoulder Center, Indianapolis
MissouriUniversity of Missouri Department of Orthopaedic Surgery, Columbia
Washington University in St Louis, Department of Orthopedic Surgery, St Louis
OhioThe Ohio State Univeristy - Department of Plastic and Reconstructive Surgery, Columbus
WashingtonHarborview Medical Center - University of Washington, Seattle

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.