Home › Cervical Cancer › NCT06872346
Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice, RCT
Personalized Risk-based Follow-up of Cervical Cancer Screening in Practice (PREDICT), Randomized Control Trial
Who can join
Ages 21 to 70 · Women
Full eligibility criteria
Inclusion Criteria, Individuals who: * have a cervix and are 21-70 years old * receive care at a participating primary care practice (i.e. PCP team visit within past 3 years) * have had a Pap and/ or HPV test within the past 3.5 years * has a CCSM result that suggest a 5-year risk of developing CIN3+ that warrants surveillance at 1 or 3 years, diagnostic colposcopy, or treatment (i.e., above average risk). Inclusion of those up to age 70 is intended to identify individuals whose prior history does not meet screening exit criteria, and warrants surveillance or diagnostic care even though women with adequate prior screening can stop at age 65 Exclusion Criteria Individuals who: * were diagnosed with cervical cancer/ CIN3+ prior to the most recent screening Pap or HPV test * have had their cervix removed * are not English or Spanish-speaking.
About the study
The goal of this PREDICT is to assess a personalize approach to screening and management of cervical cancer testing. The investigators will evaluate patients who are due for a follow up cervical cancer screening in the primary care clinics in the Massachusetts General Brigham system. Patients will be randomized by clinic into three different arms (Arm 1: standard care, Arm 2: visit based reminders, Arm 3: visit based reminders and population health outreach)
What is being tested
- Visit-based IT reminders to patients and practitioners (other)
- Population outreach (other)
Sponsor: Massachusetts General Hospital · Participants: 7,500 · Started: Jul 22, 2026
Contact the study team
- Jennifer S Hass, MD · Phone: 617-724-1832
Official record on ClinicalTrials.gov — NCT06872346
Locations in the U.S.
| Massachusetts | Massachusetts General Brigham, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.