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Study of an Oral Fluid Testing Approach
Oral Fluid Testing to Assess Cannabis Non-Use in Remote Clinical Trials
Who can join
Ages 18 to 30 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age 18 to 30 years * Cannabis use on \>=1x/week in the past 30 days * Ownership of a portable device that is capable of videoconference and videorecording (i.e., smartphone, tablet computer, or laptop computer) * Ability to read and speak English * Availability for duration of the study (3-4 weeks). * To proceed to oral fluid testing, positive result for urinary TCH-COOH Exclusion Criteria: • Inability/unwillingness to provide contact information Individuals age 18-30 are invited to screen here: https://redcap.link/softa-bch
About the study
The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely. The researchers will conduct this fully virtual study among a community sample of 200 individuals aged 18-30 years who have used cannabis at least 1 time per week on average in the past 30 days. Participants will complete oral fluid (saliva) tests, urine tests, and Timeline Follow-back interviews (self-report) that indicate their recent cannabis use (delta-9-THC). Participants will present for 3 virtual study visits across \~ 3-4 weeks and be asked to complete activities in between: Study Visit 1 (Day 0; informed consent, baseline survey, TLFB interview), Study Visit 2 (\~ Day 7; TLFB interview, urine testing), 6 days of at-home videorecorded oral fluid testing, Study Visit 3 (\~ Day 21; TLFB interview, urine test, oral fluid test, survey, interview).
Individuals age 18-30 are invited to screen here: https://redcap.link/softa-bch
What is being tested
- Biologic testing for THC (other)
Sponsor: Boston Children's Hospital · Participants: 200 · Started: Oct 27, 2025
Contact the study team
- Foday Nabbie · Phone: 617-355-2525
- Madison M O'Connell, MPH · Phone: 617-919-6964
Official record on ClinicalTrials.gov — NCT06891235
Locations in the U.S.
| Massachusetts | Boston Children's Hospital, Boston |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.