Home › Abdominal Obesity › NCT06891534

Circadian Rhythms in Human Adipose

Circadian Regulation of Human Adipose Tissue Metabolism

Who can join

Ages 18 to 55 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* BMI 20-25 kg/m2 or 30-37 kg/m2
* For participants with obesity a waist-to-hip ratio of ≥0.95 in males and ≥0.90 in females.
* sedentary
* females: non pregnant or breastfeeding
* ability to provide written informed consent and follow study instructions

Exclusion Criteria:

* History of mediations that impact adipocyte/lipid metabolism
* smoking
* insomnia
* sleep apnea
* sleep medication use
* employment in night or shift work
* extreme chronotypes
* Allergy to lidocaine

About the study

The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.

What is being tested

• Continuous Feeding (other)
• Intermittent feeding (other)

Sponsor: Mayo Clinic · Participants: 40 · Started: Jul 1, 2021

Contact the study team

• Kelli A Lytle, PhD · Phone: 507-255-1488

Official record on ClinicalTrials.gov — NCT06891534

Locations in the U.S.

Conditions

• Abdominal Obesity
• Obesity

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.