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Diffusion MRI for Quantitative Assessment of Myofascial Pain

RecruitingObservational studyHealthy volunteers welcome

Development of RPBM for Quantitative Assessment of Myofascial Pain

Who can join

Ages 18 to 65 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Men and women 18-65 years of age
* Ability to give informed consent
* Symptoms meeting criteria for normal or latent/active temporomandibular myofascial pain

Exclusion Criteria:

* Contraindications to MRI scanning including severe obesity or difficulty in laying in a supine position, intracranial clips, metal implants, external metallic devices/objects/clips within 10mm of the head, suspected or confirmed metal in the eyes (history of welding or similar activity), claustrophobia, cardiac pacemaker or pacing wires
* Pregnancy or breast feeding
* Traumatic injury of masticatory muscles or temporomandibular joint within last 12 months
* Mandibular fracture within last 12 months
* Initiation of additional treatment of myofascial pain within the past 1 month
* Received masseter Botox within the last 4 months

About the study

The purpose of this study is to assess the diagnostic accuracy of diffusion MRI for evaluation of the jaw muscles for patients with masticatory myofascial pain syndrome.

Sponsor: Weill Medical College of Cornell University · Participants: 90 · Started: Sep 4, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06892041

Locations in the U.S.

New YorkNew York University, New York
Weill Cornell Medicine, New York

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.