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Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty

Evaluating the Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty: A Randomized Control Trial

Who can join

Ages 18 to 79 · All sexes

Inclusion Criteria:

* Skeletally mature patients (ages 18-79) undergoing primary total shoulder arthroplasty

Exclusion Criteria:

* Patients with Cancer, venous thromboembolism, stroke, heart disease, pregnant or nursing, allergic to TXA, current tobacco use, anticoagulants other than aspirin.

About the study

The purpose of this clinical trial is to evaluate the short-term clinical outcomes of patients undergoing total shoulder arthroplasty who receive an extended postoperative course of oral tranexamic acid

What is being tested

• oral tranexamic acid (drug)
• Placebo (drug)

Sponsor: University of Alabama at Birmingham · Participants: 60 · Started: Apr 20, 2026

Contact the study team

• Walter Smith · Phone: 205-930-8554

Official record on ClinicalTrials.gov — NCT06902714

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.