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BoTox Into the Sternocleidomastoid Muscles (SCM)

The Effect of Injection of prabotulinumtoxinA-xvfs (Jeuveau) Into the Bilateral Sternocleidomastoid Muscles on Neck Circumference and Aesthetics

Who can join

Ages 18 to 65 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Age eligible individual seeking a more feminine neck appearance

Exclusion Criteria:

* Prior neuromodulator injections in the sternocleidomastoid muscles (SCM) within the past year
* Current anticoagulant use
* Body mass index (BMI) \>30
* Anticipation of significant weight gain or loss during the study period (e.g. patients taking or planning to take within the study period a semaglutide medication.)
* Prior allergy to botulinum toxin A
* Currently pregnant or breastfeeding

About the study

Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms. In this study botulinum toxin will be injected into the SCM to determine if this will result in a temporary slimming effect on the neck and produce a more feminine, youthful neck contour.

What is being tested

• prabotulinumtoxinA-xvfs (drug)

Sponsor: Boston Medical Center · Participants: 30 · Started: May 14, 2025

Contact the study team

• Jeffrey Spiegel, MD · Phone: 617 566-3223
• Amanda Goslawski, MD · Phone: 617 638-7934

Official record on ClinicalTrials.gov — NCT06903975

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.