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Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells

Who can join

Ages 18 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Adults aged 18 or older

Exclusion Criteria:

* Pregnant
* Prisoner or in police custody
* Uncontrolled hyperglycemia/diabetes
* Current participation in another study where the total volume of blood drawn, when added to this study blood draw volume, exceeds 500cc in an 8 week period
* Any medical issue or pharmacologic exposure which, in the opinion of the study investigator, that might interfere with the study objectives
* Any reason which, in the opinion of the study investigator, adds additional risk to the participant

About the study

The purpose of this study is to understand how cells of the immune system use the common sugar glucose to fuel energy production and as a building block within the cell. Investigators will intravenously infuse a non-radioactive glucose tracer into participants over a few hours and collect immune cells from the blood to track uptake and usage of this glucose within these immune cells.

What is being tested

• 13C6-Glucose (drug)

Sponsor: Vanderbilt University Medical Center · Participants: 12 · Started: Oct 1, 2025

Contact the study team

• Matthew T Stier, M.D., Ph.D. · Phone: 615-875-4978

Official record on ClinicalTrials.gov — NCT06930976

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.