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Occupational Cancer Screening in Firefighters: A Pilot Study Within the Inova Health System
Who can join
Ages 35 to 85 · All sexes
Full eligibility criteria
Inclusion Criteria: * Age ≥ 35 years old * at least 10 cumulative years working as a firefighter * Actively serving as a firefighter (active or volunteer) with completion of NFPA physical examination within the past 6 months * Ability to understand and willing to sign informed consent * Ability to understand and willing to sign the Health Insurance Portability and Accountability Act (HIPAA) Authorization * Additional eligibility criteria in protocol Exclusion Criteria: * No prior history of any invasive cancer within the previous 5 years (non-melanoma skin cancer and in situ carcinoma would still be eligible) and no current diagnostic workup for suspicion of cancer * Received a whole-body MRI, whole-body ultrasound, or been tested with a MCD within the past 1-year * For women of childbearing potential, pregnancy and no plans for pregnancy for the duration of the study * Additional exclusion criteria in protocol
About the study
The purpose of this study is to further understand the clinical impact and follow-up steps that may be required based on using whole-body Magnetic Resonance Imaging (MRI) or whole-body ultrasound and blood tests to detect multiple cancers in firefighters.
This study involves an investigational test (cancer blood test) that has not been approved by the U.S. Food and Drug Administration (FDA).
Whole-body MRI and whole-body ultrasound are approved by the U.S. Food and Drug Administration (FDA) to be used in the diagnosis of some cancers and is approved for adults and children who present other signs of potential disease. In this study, however, the whole-body MRI and the whole-body ultrasound are considered investigational devices because they are not yet approved for use in healthy adults with no other cancer indications.
What is being tested
- Whole Body MRI (procedure)
- Whole Body Ultrasound (procedure)
- MCD Assay (device)
- Occupational Exposure Questionnaire (other)
Sponsor: Inova Health Care Services · Participants: 800 · Started: Feb 11, 2025
Contact the study team
- Salman Baig · Phone: (571) 472-3500
- Bryan Bassig, PhD · Phone: (571) 472-3500
Official record on ClinicalTrials.gov — NCT06931561
Locations in the U.S.
| Virginia | Inova Schar Cancer - Saville Cancer Screening and Prevention Center, Fairfax |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.