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Optimizing Aerobic Fitness in Older Adults

Recruiting

Optimizing Aerobic Fitness and Functional Response to Exercise in Older Adults

Who can join

Ages 65 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* \>65 years old
* ambulatory
* enrolled in CR at our center following a recent clinical diagnosis of myocardial infarction or percutaneous intervention will be recruited

Exclusion Criteria:

* have an active malignancy (excluding non-melanoma skin cancer or low grade prostate cancer under surveillance)
* unwilling to comply with the exercise prescription they may be assigned to
* have a submaximal performance on entry exercise tolerance test, defined as respiratory exchange ratio \<1.0

About the study

Hospitalization and treatment for cardiovascular disease is one of the main contributors to disability in older adults. Moderate intensity continuous aerobic and resistance training have been the cornerstone of cardiac rehabilitation (CR) for decades to remediate hospital-acquired functional deficits, but some groups receive less or minimal functional benefit from this training. The proposed studies seek to optimize recovery of aerobic fitness and physical function among older cardiac patients using a novel high intensity training regimen with the long-term goal of reducing subsequent disability and improving clinical outcomes.

What is being tested

Sponsor: University of Vermont Medical Center · Participants: 114 · Started: Apr 17, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06951620

Locations in the U.S.

VermontUVMMC Cardiac Rehabilitation, South Burlington

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.