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Evaluating the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

RecruitingPhase 3

A Multicenter, Double-Blind, Randomized Study to Evaluate the Effects of Tasimelteon vs. Placebo in Treating Pediatric Insomnia

Who can join

Ages 2 to 17 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Ability and acceptance to provide written informed consent of the participant or legal guardian (and assent as required).
* Confirmed clinical diagnosis of insomnia disorder
* Males and Females between 2 and 17 years, inclusive.
* The sleep disturbance must not be a result of another medication.

Exclusion Criteria:

* Inability to dose daily with tasimelteon or previous intolerance to tasimelteon.
* Indication of impaired liver function.
* Pregnant or lactating females.
* A positive test for drugs of abuse.

About the study

This is a multicenter, double-blind, randomized study to evaluate the efficacy and safety of a daily single oral dose of tasimelteon and matching placebo in male and female pediatric participants with insomnia disorder.

What is being tested

Sponsor: Vanda Pharmaceuticals · Participants: 420 · Started: Apr 21, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06953869

Locations in the U.S.

AlabamaVanda Investigational Site, Dothan
ArizonaVanda Investigational Site, Phoenix
CaliforniaVanda Investigational Site, Irvine
FloridaVanda Investigational Site, Miami
Vanda Investigational Site, Miami Lakes
Vanda Investigational Site, Winter Park
GeorgiaVanda Investigational Site, Snellville
Vanda Investigational Site, Stockbridge
IllinoisVanda Investigational Site, Naperville
MassachusettsVanda Investigational Site, Worcester
MontanaVanda Investigational Site, Great Falls
NevadaVanda Investigational Site, Las Vegas
OhioVanda Investigational Site, Cleveland
South CarolinaVanda Investigational Site, Columbia
Vanda Investigational Site, Myrtle Beach
TennesseeVanda Investigational Site, Nashville
TexasVanda Investigational Site, Houston
Vanda Investigational Site, Plano
Vanda Investigational Site, San Antonio
Vanda Investigational Site, San Antonio

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.