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Healthy Volunteers Study
Vaginal Metabolome Healthy Volunteers Study
Who can join
Ages 30 to 50 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * has ovaries Exclusion Criteria: * genetic mutations which increase risk of ovarian cancer: BRCA1/2, BRIP1, PALB2, Lynch Syndrome (MLH1, MSH2/EPCAM, MSH6) and ATM * no genetic testing results or unknown genetic status * prior cancer diagnosis * prior cancer treatment * HRT use * Antibiotic use (1 month prior to providing sample)
About the study
The purpose of this study is to examine the role of the bacterial environments and metabolites in the early detection and prediction of ovarian cancer development. Vaginal swabs and stool samples will be collected from healthy volunteers, or those without a known ovarian cancer diagnosis or genetic ovarian cancer risk. These samples will be compared to samples from participants with increased cancer risk and ovarian cancer diagnoses.
What is being tested
- Self-Administered Sample Collection (other)
Sponsor: Abramson Cancer Center at Penn Medicine · Participants: 50 · Started: Apr 21, 2025
Contact the study team
- Catherine Wolfe, BA · Phone: 215-360-0422
- Jamie Brower, MS · Phone: 215-662-7245
Official record on ClinicalTrials.gov — NCT06962059
Locations in the U.S.
| Pennsylvania | Abramson Cancer Center of the University of Pennsylvania, Philadelphia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.