4-day Plaque Accumulation Model Evaluating Compound Containing Gum

Inclusion Criteria:

* Adult subjects between 18 and 65 years old
* Willing to read and sign the IRB-approved informed consent.
* Healthy, as determined by pertinent medical history at the study dentist's discretion.
* A minimum of 20 natural teeth (excluding third molars) with at least two scorable surfaces per tooth (teeth with full crowns, large/extensive restorations on the interproximal areas, and orthodontic bands will not be included in the tooth count)
* PLI of 2 or greater (Based on the Turesky modification of the Quigley and Hein Plaque Index) calculation based on a whole mouth plaque score.
* Willing to comply with the study procedures.

Exclusion Criteria:

* Presence of any acute or chronic condition, organ system disease, or medication that, in the principal investigator's opinion, could compromise the subjects' ability to participate in the study.
* Gross oral pathologies, including caries, calculus, or soft tissue conditions that show evidence of chronic neglect.
* Evidence of acute periodontal conditions or periodontitis with pockets greater than 5 mm on more than one site
* Use of antibiotics 30 days prior to or during the study
* Requiring the need for antibiotic premedication prior to dental procedures
* Sensitivity to bovine products (lactoferrin) or any of the listed inactive ingredients
* Orthodontic appliances or any removable, except lingual bar retainers
* Self-reported pregnant, wanting to get pregnant, or breast-feeding female,
* Self-reported allergy to disclosing solution ingredients (red dye #28)
* Acute Temporomandibular Disorders (TMD)
* Subject who has participated in other studies (including non-medicinal studies) involving product(s) within 30 days before study screening.
* Subject who has previously been randomized in this study
* An employee of the study site directly involved with the study