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Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)

RecruitingObservational study

A Prospective Study to Assess the Prevalence of Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC) Patients With Weight Loss

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Men, Women, and all genders
* Individuals 18 years old or older are included.
* Patients of the study investigators and team members
* Diagnosis of pancreatic ductal adenocarcinoma
* All subjects must consent to this study
* Clinically diagnosed weight loss

Exclusion Criteria:

* Minors
* Pregnant Women
* Any records flagged "break the glass" or "research opt out."
* Patients who have received treatment for SIBO in the past 3 months

About the study

The purpose of this study is to prospectively analyze the prevalence of SIBO in patients with Pancreatic adenocarcinoma (PDAC) and understand its association with weight loss and pancreatic resection status. Each patient will be tested for SIBO using Lactulose Hydrogen Breath Test. 100 patients with diagnosed pancreatic adenocarcinoma and clinically diagnosed weight loss will be enrolled in this study.

Sponsor: Cedars-Sinai Medical Center · Participants: 100 · Started: Apr 14, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT06988150

Locations in the U.S.

CaliforniaCedars-Sinai Medical Center, Los Angeles

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.