Home › NCT06991400
Evaluation of Laparotomy With Trans-Amniotic Suture Placement in TTTS Surgery
Recruiting
Who can join
Ages 18 and older · Women
Full eligibility criteria
Inclusion Criteria: * Diagnosis of TTTS or Twin Anemia-Polycythemia Sequence (TAPS) * Gestational age between 18 weeks and 23 weeks (18 0/7 to 22 6/7 weeks) * Cervical length \>2.5 cm preoperatively * Identification of a safe percutaneous surgical window by a provider experienced in fetoscopic surgery prior to entering the operating room Exclusion Criteria: * Higher order pregnancies, chromosomal or severe congenital anomalies, undergoing laser surgery for fetal growth restriction only, need for a second laser during pregnancy, failure to complete laser, PPROM prior to surgery. BMI\> 40 at the start of pregnancy, emergent case (i.e. surgery occurs \< 6 hours from presentation), significant fetal anomalies expected to drastically alter the risk of neonatal morbidity or mortality (i.e. anencephaly, cyanotic heart disease), or any significant maternal comorbidities as determined by physician i.e.: clotting disorders/blood disorders.
About the study
This is a randomized trial for patients that are diagnosed with Twin-Twin Transfusion Syndrome (TTTS) who are receiving a fetoscopic laser surgery to evaluate the effectiveness and safety of a laparotomy closure.
What is being tested
- Trans-Amniotic Suture Placement (other)
Sponsor: Children's Hospital Medical Center, Cincinnati · Participants: 34 · Started: Nov 1, 2024
Contact the study team
- Kimberly Richards · Phone: 513-636-2310
- Erin Watters · Phone: 513-803-7024
Official record on ClinicalTrials.gov — NCT06991400
Locations in the U.S.
| Ohio | Cincinnati Childrens Hospital Medical Center, Cincinnati |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.