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Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Web-based Technology and Cognitive Training: Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Who can join

Ages 60 to 75 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Age 60-75
* Adequate English proficiency
* Willingness to adhere to training protocol:

  * Attend 2 in-person assessments
  * Attend a blood test
  * Attend online intervention sessions and online follow-up assessment

Exclusion Criteria:

* Low test scores (below 26 on the Montreal Cognitive Assessment)
* Known history of cognitive impairment, dementia, stroke, seizure disorder, or other neuropsychiatric condition judged to impact cognitive performance.
* Taking medications known to influence cognitive performance.
* Sensory (e.g. visual, auditory) or physical (e.g. severe arthritic, orthopedic, neurologic) impairment incompatible with use of a standard computer workstation.
* Enrolled in a concurrent study that could affect the outcome of this study.

About the study

Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk. Executive Control is a relevant cognitive target since it declines with aging and is critical for multi-tasking in daily life. The proposed research investigates whether playing a web-based cognitive complex game (the Breakfast Game) impacts cognitive performance in cognitively healthy older adults. To be enrolled in the study, participants will be asked to undergo a cognitive sassessment, health questionnires, and a blood exam. The intervention consist in one educational session on healthy aging, and 10 one-hour cognitive training sessions 2-3 times a week over one month. Participants will be asked to repeat the cognitive assessment within 1-2 weeks after the intervention, and after three months.

What is being tested

• Web-based Cognitive Training (with strategy) (behavioral)
• Web-based Cognitive Training (without strategy) (behavioral)

Sponsor: Rutgers, The State University of New Jersey · Participants: 130 · Started: Dec 10, 2025

Contact the study team

• Thamiris Golçalves Clinical Research Coordinator, MS · Phone: 973-972-2977

Official record on ClinicalTrials.gov — NCT06995638

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.