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Effect of Prolonged Fasting Time on Gastric Residual Volume in Patients Taking GLP1 Receptor Agonists

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Patients undergoing elective upper endoscopy with gastroenterology team

Exclusion Criteria:

* Urgent or emergent procedure
* Inclusion of colonoscopy or antegrade small bowel enteroscopy in planned procedure
* Upper GI barium study performed in past 24 hours.
* Gastroparesis
* Achalasia
* Pancreatitis
* Use of outpatient pro-motility medications
* Patient refusal
* Inability for patient to provide own consent

About the study

The aim of this study is to determine whether a modified fasting protocol can reduce the potential risk of aspiration for patients currently prescribed GLP1-RAs.

What is being tested

• Modified Fasting Guidelines (other)

Sponsor: Mayo Clinic · Participants: 150 · Started: Aug 1, 2025

Contact the study team

• Krishnan Ramanujan, MD · Phone: 507-422-4898

Official record on ClinicalTrials.gov — NCT07006142

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.