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Assistance Delivery and Muscle Coordination

RecruitingEarly phase 1Healthy volunteers welcome

Who can join

Ages 20 to 80 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria for stroke survivors:

* Age: 18 - 70 years old
* First-ever unilateral cortical stroke with resultant hemiparesis at least 6 months prior to the experimental testing
* Fugl-Meyer Upper Extremity Section 31 - 55

Exclusion Criteria for both stroke and control:

* Presence of concurrent severe medical illness
* Pain in hand or arm with movements
* Loss of voluntary control of fingers and thumb
* Inability to provide informed consent
* Musculoskeletal injuries (e.g., fracture) or medical complications (e.g., severe cardiovascular disease).

About the study

The experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform extension movements of the index finger of their more-impaired (stroke) or nondominant (control) hand under two different assistance types: end-effector assistance and exotendon assistance. For each assistance type, unassisted movements will be performed before and after the assistance. Subjects will be randomly assigned into two groups (A and B), who will receive the assistance in a different order. The finger movements and muscle activation patterns will be recorded during movements.

What is being tested

Sponsor: The Catholic University of America · Participants: 30 · Started: Nov 21, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT07011173

Locations in the U.S.

District of ColumbiaCatholic University of America, Washington D.C.

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.