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Patient Navigation and the Planning Advance Care Together Website to Improve Goals of Care Conversations in Hematopoietic Cell Transplant Survivors, IMPACT-HCT Trial

Improving Goals of Care Conversations With Hematopoietic Cell Transplant Survivors (IMPACT - HCT)

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Received a transplant for a hematologic malignancy
* Current age 18 years of age or older
* Currently 1 to 5 years after HCT
* Ability to speak and read English
* Has not completed all advance directives and/or had a goals of care (GOC) conversation with their physician
* Access to the internet (via computer, tablet, or mobile device)

Exclusion Criteria:

* Unable to provide informed consent
* Uncontrolled psychiatric conditions (confirmed through electronic health record \[EHR\] by study staff)

About the study

This clinical trial evaluates the impact of patient navigation and the Planning Advance Care Together (PACT) website, either alone or in combination with one another, on advanced care planning (ACP) in patients with blood cancers who received a hematopoietic cell transplant (HCT). Engagement in ACP, including having goals of care conversations, improves quality of care at the end of life and supporting this should be included in all cancer survivorship care. Patient navigation is a healthcare service that is designed to guide a patient through the healthcare system and reduce barriers to timely screening follow-up, diagnosis, treatment, and supportive care. PACT is a web-based tool that provides information about ACP, assistance with documents for advanced directives, a supportive network and a forum for discussions about ACP. Patients who engage in ACP are more likely to have higher quality of life at the end of life, receive the care they want, die where they prefer, utilize hospice effectively, and are less likely to receive futile, aggressive care at the end of life. For HCT survivors at ongoing risk of death and other disease-related complications, having a plan in place for care they want is critical. Patient navigation and/or the PACT website may improve ACP, including completion of advance care directives and goals of care conversations, in patients with blood cancers who received an HCT.

What is being tested

• Internet-Based Intervention (other)
• Patient Navigation (behavioral)
• Best Practice (other)
• Survey Administration (other)

Sponsor: Fred Hutchinson Cancer Center · Participants: 40 · Started: Oct 21, 2025

Contact the study team

• Megan Shen, PhD · Phone: 206-667-4172

Official record on ClinicalTrials.gov — NCT07052630

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.