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The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness

The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness. A Randomized Controlled Trial.

Who can join

Ages 18 to 18 · All sexes · Healthy volunteers welcome

Inclusion Criteria:

1. Ability of subject to understand and the willingness to sign a written informed consent document.
2. Males and females; Age 18 to 89 years old
3. Require second stage implant uncovering
4. In either the maxillary or mandibular arch
5. Has consistent transportation for all clinical and study visits

Exclusion Criteria:

1. Pregnancy, or those planning to become pregnant
2. Allergy or any medical issue using EMD
3. Non-English speaking
4. Patients on anticoagulants
5. Patients who object to the use of animal products

About the study

Scientists do research to answer important questions which might help change or improve the way we do things in the future.

The investigators know that using Enamel Matrix Derivatives results in thicker gum tissues around teeth. This study will test to see if using EMD around implants results in thicker gum tissues around implants.

What is being tested

• Enamel Matrix Derivative (device)

Sponsor: The University of Texas Health Science Center at San Antonio · Participants: 32 · Started: Aug 31, 2025

Contact the study team

• Angela Palaiologou-Gallis, DDS · Phone: 210-450-3715

Official record on ClinicalTrials.gov — NCT07053969

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.