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Assessment of Circuit Rebreathing During CPAP Therapy

Recruiting

Assessment of Circuit Rebreathing During Continuous Positive Airway Pressure (CPAP) Therapy

Who can join

Ages 21 to 70 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Moderate to severe OSA (AHI\>20)
* Self-reported CPAP users or have previously used CPAP
* Self-reported holding pressure of maximum 13 cmH2O (if known)
* Age: 21-70
* BMI: 18-40 kg/m2

Exclusion Criteria:

* Self-reported severe mouth-breathing
* Requirement for nocturnal supplemental oxygen or other ventilatory support
* Severe cardiovascular or pulmonary disease
* Any unstable or acute medical condition
* Any additional sleep disorder, including insomnia, except for OSA.

About the study

The goal of this research is to better understand how different CPAP mask designs affect airflow and rebreathing of exhaled carbon dioxide (CO₂) during sleep in individuals with obstructive sleep apnea (OSA).

What is being tested

Sponsor: Brigham and Women's Hospital · Participants: 13 · Started: May 27, 2025

Contact the study team

Official record on ClinicalTrials.gov — NCT07062770

Locations in the U.S.

MassachusettsBrigham and Women's Hospital, Boston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.