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Bioavailability of Ration Items Containing Tart Cherry Extract

RecruitingHealthy volunteers welcome

Who can join

Ages 17 to 39 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Active duty military personnel and civilians will be invited to participate in the study if they:

  * Are between the ages of 18 (or 17 for military personnel) and 39.
  * Are willing to participate in all study procedures and comply with all study instruction.
  * In good health as determined by OMSO (Office of Medical Support and Oversight).
  * Supervisor approval for federal civilian employees and non-HRV active-duty military personnel stationed at NSSC

Exclusion Criteria:

* • Unable to understand verbal or written instructions or testing materials in English.

  * Have a bleeding disorder (e.g., von Willebrand Disease, hemophilia) or are being treated with medication that will impair blood clotting (for example, coumadin)
  * Have a history of GI-related conditions that may impact macronutrient absorption (e.g., Crohn's disease, ulcerative colitis, Celiac's disease or gluten sensitivity, bariatric surgery or gastroparesis, short bowel, inflammatory bowel disease, etc…);
  * Any use of antibiotics or antifungal, except topical antibiotics/antifungals within 3 months of study participation.
  * Colonoscopy within 3 months of study participation.
  * Regular (i.e., weekly or more frequent) use of over-the-counter medications (including antacids, laxatives, stool softeners, and antidiarrheals) unless approved by OMSO and study PI.
  * Are habitually taking nonsteroidal anti-inflammatory drugs (e.g., Advil, aspirin), corticosteroids (e.g., prednisone) or immunosuppressants (e.g. Humira);
  * Have an allergy or aversion (extreme dislike) to any of the test foods(e.g., cherry flavored beverages or bar). Allergy symptoms may include anaphylaxis, hives or eczema, tingling/itching in the mouth, dizziness or fainting, diarrhea, nausea or vomiting, swelling of the lips, face, tongue and throat).
  * Have donated blood within the past 8 weeks of the first test session or plan to donate blood during the study.
  * Are not willing to abstain from tobacco products and vigorous exercise for at least 24 hours" before each trial and consume a low-polyphenol diet two days prior to each test session and on the day of the test session.

About the study

To determine how consuming food items containing shelf-stored tart cherry impacts your body's ability to absorb and use the compounds within tart cherry.

What is being tested

Sponsor: United States Army Research Institute of Environmental Medicine · Participants: 15 · Started: Jun 14, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT07063173

Locations in the U.S.

MassachusettsUSARIEM, Natick

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.